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Gary Cooper

Henry Louis 'Lou' Gehrig

Emory Parnell

Chicago Policeman O'Doul (uncredited)

Walter Brennan

Sam Blake

Addison Richards

Coach

Wilbur Mack

Man Outside Yankee Stadium (uncredited)

Colin Kenny

Yankee Player on Train (uncredited)

Frank Faylen

Yankee Third Base Coach (uncredited)

Earle Hodgins

Bottle Game Operator (uncredited)

Teresa Wright

Eleanor Twitchell

Harry Harvey

Joe McCarthy

Eddie Hall

Reporter in Hospital Room (uncredited)

Charles Williams

Little Strength Machine Contestant (uncredited)

Dan Duryea

Hank Hanneman

Virginia Gilmore

Myra Tinsley

Edgar Barrier

Hospital Doctor

Dane Clark

Fraternity Boy (uncredited)

Anita Sharp-Bolster

Sasha's Mother (uncredited)

Edward Peil Sr.

Policeman (uncredited)

Guy Wilkerson

Sportsman at Ballgame (uncredited)

Mitchell Ingraham

Barber (uncredited)

Heinie Conklin

Wallpaper Hanger (uncredited)

James Westerfield

Spectator (uncredited)

Rex Lease

Spectator (uncredited)

John Sheehan

First Paper Hanger (uncredited)

Lane Chandler

Mark - Player in Locker Room (uncredited)

David Holt

Billy (Age 17)

Matt McHugh

Strength Machine Operator (uncredited)

Hardie Albright

Van Tuyl

John Kellogg

Fraternity Boy (uncredited)

Lynton Brent

Photographer in Hospital (uncredited)

Edward Fielding

Clinic Doctor

John Ince

Man in Box Seat (uncredited)

Pat Flaherty

Yankee Ballplayer (uncredited)

Walter Fenner

Dentist (uncredited)

Tom Neal

Fraternity Boy (uncredited)

Lester Dorr

Disappointed Fan #1 (uncredited)

Harry Hayden

Department Store Manager (uncredited)

Mary Gordon

Maid (uncredited)

Don Brodie

Girl Show Barker (uncredited)

Cyril Ring

Photographer (uncredited)

Pierre Watkin

Mr. Twitchell

Eddy Chandler

Motorcycle Cop #2 (uncredited)

Charles Cane

Plumber (uncredited)

Wilmuth Merkyl

Spectator (uncredited)

Vinton Hayworth

Fraternity Boy (uncredited)

Ernie Adams

Miller Huggins

Douglas Croft

Lou Gehrig as a Boy

Hooper Atchley

Lathered Man in Barber Shop (uncredited)

Ludwig Stössel

Henry 'Pop' Gehrig

Janet Chapman

Tessie (uncredited)

Elsa Janssen

Christina 'Mom' Gehrig

Babe Ruth

George Offerman, Jr.

Freshman (uncredited)

Spencer Charters

Mr. Larsen (uncredited)

Jack Stewart

Ed Barrow (uncredited)

George Guhl

Second Paper Hanger (uncredited)

Malcolm Waite

Big Strength Machine Contestant (uncredited)

Dorothy Vaughan

Eleanor's Landlady (uncredited)

Theodore Lorch

Neighbor Leaning Through Window (uncredited)

Dorothy Vernon

Family Friend (uncredited)

Art Rowlands

Telephone Man (uncredited)

Clancy Cooper

Motorcycle Cop #1 (uncredited)

Charles Irwin

Carnival Batting Game Operator (uncredited)

Ben Taggart

Conductor (uncredited)

Edwin August

Restaurant Patron (uncredited)

Sarah Padden

Mrs. Roberts (uncredited)

Walter Tetley

Cake Delivery Boy (uncredited)

Howard M. Mitchell

Sportsman at Ballgame (uncredited)

Vaughan Glaser

Doctor in Gehrig Home (uncredited)

Yolanda

Specialty Dancer (as Veloz and Yolanda)

William Roy

Joe Fabrini (uncredited)

Donald Kerr

Photographer (uncredited)

Rosina Galli

Mrs. Fabrini (uncredited)

Betty Brewer

Little Girl (uncredited)

Garry Owen

Scorecard Vendor (uncredited)

Fay Holderness

Spectator (uncredited)

George Lessey

Mayor of New Rochelle

Veloz

Specialty Dancer (as Veloz and Yolanda)

C. Montague Shaw

Mr. Worthington (uncredited)

Ray Noble

Orchestra Leader (uncredited)

Bill Dickey

Bob Meusel

Robert W. Meusel (as Robert W. Meusel)

Mark Koenig

Bill Stern

Gene Collins

Billy (Age 8)

Ed Agresti

Barber (uncredited)

Ernie Alexander

Bellhop with Flowers (uncredited)

Bettye Avery

Nightclub Singer (uncredited)

Becky Bohanon

Little Girl (uncredited)

Roy Brent

Yankee Ballplayer (uncredited)

Jack Carr

Plumber (uncredited)

Burr Caruth

Village Storekeeper (uncredited)

Bill Chaney

Newsboy (uncredited)

Jack Chapin

Photographer (uncredited)

Porter Chase

Weight Guesser (uncredited)

Hal Cooke

Man in Cab (uncredited)

John Daheim

Reporter in Hospital (uncredited)

Eva Dennison

Mrs. Worthington (uncredited)

Peter Du Rey

Photographer in Hospital (uncredited)

Lorna Dunn

Clinic Nurse (uncredited)

Jim Farley

Spectator (uncredited)

Dick Gordon

Radio Listener (uncredited)

Herschel Graham

Spectator (uncredited)

Oscar 'Dutch' Hendrian

Furniture Mover (uncredited)

John Hiestand

Announcer (uncredited)

Jack Irwin

Photographer in Hospital (uncredited)

Sheldon Jett

Sportsman at Ballgame (uncredited)

Payne B. Johnson

Boy in Ball Park (uncredited)

Richard Kipling

Broker (uncredited)

Pat Lane

Wheel of Chance Barker (uncredited)

Larry Lawson

Barker (uncredited)

Frank Lyman

Fraternity Boy (uncredited)

Dave Manley

Mayor Fiorello LaGuardia (uncredited)

Maurice Marks

Player (uncredited)

Francisco Marán

Rathskeller Headwaiter (uncredited)

John C. McCallum

Minor Role (uncredited)

Ralph McCullough

Reporter in Hospital (uncredited)

George McDonald

Wally Pipp (uncredited)

James McNamara

Rathskeller Manager (uncredited)

Irving Mitchell

Headwaiter (uncredited)

Pat Moriarity

Policeman in 1915 (uncredited)

Patsy O'Byrne

Scrubwoman (uncredited)

John B. Old

Reporter (uncredited)

Tom Quinn

Reporter in Hospital (uncredited)

Henry Roquemore

Disappointed Fan #2 (uncredited)

Rip Russell

Laddie (uncredited)

Francis Sayles

Cab Driver (uncredited)

Jack Shea

Hammond (uncredited)

Brick Sullivan

Policeman (uncredited)

Jimmy Valentine

Sasha - Boy Playing Baseball (uncredited)

Gohr Van Vleck

Furniture Mover (uncredited)

Max Willenz

Mr. Colletti (uncredited)

Buddy Williams

Bootblack (uncredited)

Robert Winkler

Murphy (uncredited)

Allen Wood

Freshman (uncredited)

Mike Donovan

Charles Flynn

Fraternity Boy (uncredited)

Jack Gardner

Anthony Walters

Merril (uncredited)