Drama
Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to "awaken" the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial treatment. His awakening, filled with awe and enthusiasm, proves a rebirth for Sayer too, as the exuberant patient reveals life's simple but unutterably sweet pleasures to the introverted doctor.
Directed by
Penny Marshall
Robert De Niro
Leonard Lowe
Vin Diesel
Hospital Orderly (uncredited)
Robin Williams
Malcolm Sayer
Peter Stormare
Neurochemist
Carrie Fisher
John Heard
Dr. Kaufman
Bradley Whitford
Dr. Tyler
Vincent Pastore
Ward #5 Patient #6
Max von Sydow
Peter Ingham
Anne Meara
Miriam
Penelope Ann Miller
Paula
Julie Kavner
Eleanor Costello
Penny Marshall
Mary Alice
Nurse Margaret
Richard Libertini
Sidney
George Martin
Frank
Alice Drummond
Lucy Fishman
Steve Vinovich
Ray
Barton Heyman
Bert
Ruth Nelson
Mrs. Lowe
Keith Diamond
Anthony
Steven Randazzo
Luis
Judith Malina
Rose
Tracy Reiner
John Christopher Jones
Dr. Sullivan
Laura Esterman
Lolly
Charles Keating
Mr. Kean
Tiger Haynes
Janitor
Yusef Bulos
Joseph
Jack Mulcahy
Psych Ward Intern
Mel Gorham
Nurse Sara
Bret McCormick
Head Ward Orderly
Le Clanché du Rand
Magda
Byron Utley
Ward #5 Patient #2
Oliver Sacks
Harry L. Seddon
Medical Student
Dexter Gordon
Rolando
Mary Catherine Wright
Nurse Beth
Jayne Haynes
Frances
Gloria Harper
Dottie
Gwyllum Evans
Desmond
Harvey Miller
Hospital Director
Tanya Berezin
Psychiatrist
Shane Fistell
Man in Hall
Waheedah Ahmad
Hysterical Woman
Christina Huertes
Christina
Linda Burns
Fishsticks
Judy Jacksina
Hospital Receptionist
Rico Elias
Orderly #1
Chris Carolan
EEG Technician
Debra Kovner-Zaks
Cafeteria Nurse
Gordon Joseph Weiss
Ward #5 Patient
Anthony McGowen
Ward #5 Patient #3
Paul Montgomery
Ward #5 Patient #4
Leonard Tepper
Ward #5 Patient #5
Howard Feller
Ward #5 Patient #7
Libby Titus
Club Singer
Tomislav Novakovic
Bartender
Adam Bryant
Librarian
Anthony J. Nici
Young Leonard
Oliver Block
Leonard's Friend #1
Buck Smith
Leonard's Friend #2
Joan E. MacIntosh
Teacher
Jason W. Fuchs
Pot-Head Hippie

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