Family Comedy Action Adventure Fantasy
When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.
Directed by
Lawrence Guterman
Jeff Goldblum
Professor Brody
Tobey Maguire
Lou the Beagle (voice)
Frank Welker
Buddy (voice)
Alec Baldwin
Butch (voice)
Susan Sarandon
Ivy (voice)
Elizabeth Perkins
Mrs. Brody
Joe Pantoliano
Peek (voice)
Charlton Heston
The Mastiff (voice)
Michael Clarke Duncan
Sam (voice)
Sean Hayes
Mr. Tinkles (voice)
Miriam Margolyes
Sophie the Castle Maid
Jon Lovitz
Calico (voice)
John Michael Higgins
Ginger Kitten (voice)
Billy West
Ninja Cat #1 (voice)
Brad Loree
Danny Mann
Ninja Cat (voice)
Frank C. Turner
The Farmer
Richard Steven Horvitz
Puppy in Barn (voice)
Salome Jens
Collie at HQ (voice)
Ken Kirzinger
Gillian Barber
Factory Receptionist
Alvin Sanders
Mason Employee
Alexander Pollock
Scotty Brody
Lauren K. Robek
Pie Mom (as Kirsten Robek)
Carol Ann Susi
Sophie's Sister
Paul Pape
Wolf Blitzer (voice)
Charles Andre
Truck Driver
Pamela Perry
Yorkie Dog Owner
Myron Natwick
Mr. Mason
Mar Andersons
Guard at Gate
Jovan Nenadic
Frank Meschkuleit
Additional Performances (puppeteer)
Doris Chillcott
Mrs. Calvert
Mark Schooley
Mason Employee
Peggy Logan
Nurse
Randi Kaplan
Sophie's Sister
Mary Bogue
Sophie's Sister
Babe Dolan
Wife Passenger
Alicia Michelle
Jogger
Victor Wilson
Doberman Drill Sergeant (voice)
David Mylrea

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