Family Comedy Action Adventure Fantasy
When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.
Directed by
Lawrence Guterman
Jeff Goldblum
Professor Brody
Tobey Maguire
Lou the Beagle (voice)
Susan Sarandon
Ivy (voice)
Frank Welker
Buddy (voice)
Miriam Margolyes
Sophie the Castle Maid
Joe Pantoliano
Peek (voice)
Elizabeth Perkins
Mrs. Brody
Alec Baldwin
Butch (voice)
Charlton Heston
The Mastiff (voice)
Michael Clarke Duncan
Sam (voice)
Sean Hayes
Mr. Tinkles (voice)
Billy West
Ninja Cat #1 (voice)
Jon Lovitz
Calico (voice)
Danny Mann
Ninja Cat (voice)
John Michael Higgins
Ginger Kitten (voice)
Lauren K. Robek
Pie Mom (as Kirsten Robek)
Gillian Barber
Factory Receptionist
Frank C. Turner
The Farmer
Ken Kirzinger
Salome Jens
Collie at HQ (voice)
Richard Steven Horvitz
Puppy in Barn (voice)
Carol Ann Susi
Sophie's Sister
Brad Loree
Alvin Sanders
Mason Employee
Myron Natwick
Mr. Mason
Mar Andersons
Guard at Gate
Paul Pape
Wolf Blitzer (voice)
Alexander Pollock
Scotty Brody
Pamela Perry
Yorkie Dog Owner
Doris Chillcott
Mrs. Calvert
Mark Schooley
Mason Employee
Jovan Nenadic
Peggy Logan
Nurse
Randi Kaplan
Sophie's Sister
Mary Bogue
Sophie's Sister
Babe Dolan
Wife Passenger
Charles Andre
Truck Driver
Alicia Michelle
Jogger
Victor Wilson
Doberman Drill Sergeant (voice)
David Mylrea

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