Family Comedy
When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.
Directed by
Lawrence Guterman
Tobey Maguire
Lou the Beagle (voice)
Alec Baldwin
Butch (voice)
Frank Welker
Buddy (voice)
Jeff Goldblum
Professor Brody
Susan Sarandon
Ivy (voice)
Billy West
Ninja Cat #1 (voice)
Joe Pantoliano
Peek (voice)
Charlton Heston
The Mastiff (voice)
Elizabeth Perkins
Mrs. Brody
Mar Andersons
Guard at Gate
Miriam Margolyes
Sophie the Castle Maid
Sean Hayes
Mr. Tinkles (voice)
Jon Lovitz
Calico (voice)
Michael Clarke Duncan
Sam (voice)
Paul Pape
Wolf Blitzer (voice)
Gillian Barber
Factory Receptionist
John Michael Higgins
Ginger Kitten (voice)
Richard Steven Horvitz
Puppy in Barn (voice)
Alvin Sanders
Mason Employee
Lauren K. Robek
Pie Mom (as Kirsten Robek)
Alexander Pollock
Scotty Brody
Danny Mann
Ninja Cat (voice)
Myron Natwick
Mr. Mason
Salome Jens
Collie at HQ (voice)
Mark Schooley
Mason Employee
Doris Chillcott
Mrs. Calvert
Carol Ann Susi
Sophie's Sister
Frank C. Turner
The Farmer
Pamela Perry
Yorkie Dog Owner
Randi Kaplan
Sophie's Sister
Mary Bogue
Sophie's Sister
Babe Dolan
Wife Passenger
Charles Andre
Truck Driver
Peggy Logan
Nurse
Alicia Michelle
Jogger
Victor Wilson
Doberman Drill Sergeant (voice)

Your rating