Family Comedy Action Adventure Fantasy
When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.
Directed by
Lawrence Guterman
Frank C. Turner
The Farmer
Jeff Goldblum
Professor Brody
Joe Pantoliano
Peek (voice)
Tobey Maguire
Lou the Beagle (voice)
Susan Sarandon
Ivy (voice)
Alec Baldwin
Butch (voice)
Elizabeth Perkins
Mrs. Brody
Frank Welker
Buddy (voice)
Michael Clarke Duncan
Sam (voice)
Charlton Heston
The Mastiff (voice)
Paul Pape
Wolf Blitzer (voice)
Sean Hayes
Mr. Tinkles (voice)
Pamela Perry
Yorkie Dog Owner
Jon Lovitz
Calico (voice)
Charles Andre
Truck Driver
Mark Schooley
Mason Employee
Danny Mann
Ninja Cat (voice)
Doris Chillcott
Mrs. Calvert
John Michael Higgins
Ginger Kitten (voice)
Billy West
Ninja Cat #1 (voice)
Gillian Barber
Factory Receptionist
Miriam Margolyes
Sophie the Castle Maid
Salome Jens
Collie at HQ (voice)
Alexander Pollock
Scotty Brody
Ken Kirzinger
Alvin Sanders
Mason Employee
Lauren K. Robek
Pie Mom (as Kirsten Robek)
Richard Steven Horvitz
Puppy in Barn (voice)
Brad Loree
Carol Ann Susi
Sophie's Sister
Myron Natwick
Mr. Mason
Mar Andersons
Guard at Gate
Jovan Nenadic
Peggy Logan
Nurse
Randi Kaplan
Sophie's Sister
Mary Bogue
Sophie's Sister
Babe Dolan
Wife Passenger
Alicia Michelle
Jogger
Victor Wilson
Doberman Drill Sergeant (voice)
Frank Meschkuleit
Additional Performances (puppeteer)
David Mylrea

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